Fetal alcohol syndrome (FAS) refers to growth, mental, and physical problems in a baby when a woman consumes alcohol during pregnancy. The amount of alcohol ingested during pregnancy to cause FAS is still unknown, but women are advised to avoid alcohol and drug abuse. In the body, alcohol crosses the placental barrier, possibly stunting fetal growth or weight, creating distinctive facial stigmata, damaged neurons and brain structures, and causing other physical, mental, or behavioral problems.
Health Effects of FAS
The main effect of FAS is permanent central nervous system damage, especially to the brain. Prenatal alcohol exposure creates a range of primary cognitive functional disabilities, including poor memory, attention deficits, impulsive behaviour, and poor cause-effect reason, as well as secondary disabilities, such as mental health problems and drug addiction. These stem from underdeveloped or malformed brain cells.
Symptoms Of FAS Include:
- Growth deficiency – defined as significantly below average height, weight or both due to prenatal alcohol exposure
- Central nervous system damage, which is the primary feature of any FAS diagnosis. CNS damage can be assessed in three areas: structural, neurological, and functional impairments
- Structural abnormalities may include microcephaly (small head size) of two or more standard deviations below the average or other abnormalities in brain structure
- Neurological impairments cause general neurological damage to the central nervous system and the peripheral nervous system. These problems are expressed as diagnosable disorders such as epilepsy or other seizure disorders, or nonspecific neurological impairments, such as impaired fine motor skills, neurosensory hearing loss, poor gait, clumsiness, poor eye-hand coordination
- Facial features: several characteristic craniofacial abnormalities. The three FAS facial features are:
- A smooth philtrum – The divot or groove between the nose and upper lip flattens with increased prenatal alcohol exposure.
- Thin vermilion – The upper lip thins with increased prenatal alcohol exposure.
- Small palpebral fissures – Eye width decreased with increased prenatal alcohol exposure.
- Functional impairments are deficits, problems, delays, or abnormalities due to prenatal alcohol exposure, rather than hereditary causes or postnatal insults, which are observed in daily functioning, often referred to as developmental disabilities
Diagnosis Of Fetal Alcohol Syndrome
The following criteria qualify FAS diagnosis:
- Growth deficiency-Prenatal or postnatal height or weight (or both) at or below the 10th percentile
- FAS facial features- all three FAS facial features present
- Central nervous system damage- Clinically significant structural, neurological, or functional impairment
- Prenatal alcohol exposure- confirmed or unknown prenatal alcohol exposure
Risk Levels For Fetal Alcohol Syndrome
The “4-Digit Diagnostic Code” distinguishes confirmed exposure as High Risk and Some Risk:
- High Risk – Confirmed use of alcohol during pregnancy known to be at high blood alcohol levels delivered at least weekly in early pregnancy
- Some Risk – Confirmed use of alcohol during pregnancy with use less than High Risk or unknown usage patterns
- Unknown Risk – Unknown use of alcohol during pregnancy
- No-Risk – A confirmed absence of prenatal alcohol exposure, which rules out a FAS diagnosis
Prevention And Treatment Of Fetal Alcohol Syndrome
The only certain way to prevent FAS is to avoid alcohol drinking during pregnancy or while planning a pregnancy.
There is no cure for FAS due to the damage of permanent disability to the central nervous system. However, due to the range of damage, a possible treatment is possible depending on the CNS damage, symptoms, secondary disabilities, and needs.
Medications that are given included:
- Antidepressants– Treat problems with sadness and negativity.
- Stimulants– treat behavioral problems
- Neuroleptics-Used to treat anxiety and aggression
Fetal Alcohol Syndrome Prognosis
The primary disabilities are functional difficulties due to CNS damage. Often, these disabilities are mistaken as a behavioural problem, but the underlying CNS damage is the reason for the functional difficulty.
Some research has shown a correlation between functional problems and brain structures damaged by prenatal alcohol exposure. Examples include:
- Learning impairments associated with impaired dendrites of the hippocampus
- Impaired motor development and functioning associated with reduced size of the cerebellum
- Hyperactivity is associated with decreased size of the corpus callosum