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Facts About Promethazine


Purple Drank Promethazine is a type of phenothiazine antihistamine, and it works by changing the actions of chemicals in the brain, including histamine.  Promethazine has numerous uses, such as treating allergy symptoms, preventing motion sickness, treating nausea, and vomiting or pain after surgery.  It may also be used as a sedative or sleep aid.

Promethazine was first made available in the United Kingdom in 1951.

What are the street names?

The street names that are associated with promethazine include lean, purple sprite, sizzurp, purple drank, drank, and promo, among others.  Usually promethazine is offered in combination with codeine in the form of a cough syrup.  The cough syrup cocktail containing promethazine and codeine is mentioned by literally dozens of prolific hip-hop artists including Kanye West, Three 6 Mafia, DJ Screw, E-40, UGKD12, Eminem, Lil’ Wyte, Big Moe, Lil Boosie, Far East Movement, Paul Wall, Esham, Mike Jones, T.I., Rick Ross, Lil’ Flip, Lil’ Wayne, Ludacris, Fat Joe, Beanie Sigel, Project Pat, Chamillionaire, Lou Bega, Jim Jones, The Game, Slim Thug, Fat Pat, Frayser Boy, Gorilla Zoe, Z-RO, Youngbloodz, 8Ball, Papoose, Drake, Jae Millz, Mack Maine, Ace Hood, Gucci Mane, Plies, A$AP Rocky Tech N9ne, Trae, Young Buck, Yelawolf, and Mac Miller.

What are the effects of Promethazine?

In large doses, promethazine can result in a dissociative state, with hallucinations similar to those produced by PCP or ketamine.  Some users report that the large amount of sugar in promesthazine causes them to experience weight gain, tooth decay, and other medical symptoms.  Promethazine may inhibit cognitive abilities and may compromise one’s ability to operate a motor vehicle.


Hidden Risk: Before taking Promethazine

There are many side effects associated with promethazine, including but not limited to: twitching, tremors, drooling, trouble swallowing, problems with balance or walking, feelings of restlessness or agitation, high fever, stiffness, confusion, seizure, pale skin, fast or uneven heartbeats, rapid breathing, hallucination, nausea, pale skin, flu-like symptoms, skin rash, joint pain, unusual thoughts, vomiting, urinating less than usual or not at all, dizziness, blurred vision, dry mouth, stuffy nose, ringing in the ears, weight gain, impotence, and constipation.

Why do individuals use Promethazine?

Promethazine has various medical applications, such as pre- and post-surgery sedation and relaxation.  However, the potential for abuse is significant and abusers may use the drug just to get a recreational high.


What does detox from Promethazine involve?

Due to the fact that promethazine is usually combined with codeine, which is an opiate, detox will produce withdrawal symptoms similar to heroin or other opiates.  Withdrawal symptoms can start a few hours to one day after using Promethazine.   While withdrawal symptoms are not life threatening—as they can be with alcohol, benzodiazepines, and barbiturates—they are extremely uncomfortable, even painful.   This often drives the addict to want to use again to avoid the discomfort.  While there is no imminent threat of death from the withdrawal symptoms of Promethazine, the side effects are intense and a drug detox center is often needed to help with the symptoms.


Options for Detox

There are three basic options for codeine with promethazine detox.  You can try a cold turkey detox, either alone or with medical support.  The cold turkey detox approach entails abruptly quitting the drug, which can make someone very sick.  Detox clinics are available for drug addicts for the specific purpose of detoxifying, and they offer a wide range of medical help.  You can taper down the dosage over time or you can use a substitute opiate, like methadone or Suboxone.  If you have the benefit of medical help, which is the recommended approach, they will probably prescribe a substitute opiate and taper down the dosage with you.



While promethazine has numerous benefits if prescribed by a medical doctor, when used recreationally it can be extremely harmful, even life-threatening.  Better to save yourself the potential troubles that come with unsupervised recreational use by exercising caution and consulting with medical professionals before deciding whether to use promethazine or any other antihistamine.


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Filed under: Alcohol and Drugs · Tags: "Drank", 8Ball, A$AP Rocky Tech N9ne, Ace Hood, Beanie Sigel, Big Moe, Chamillionaire, codeine, D12, detox, detoxification, dissociation, DJ Screw, Drake, drug detox, E-40, Eminem, Esham, Far East Movement, Fat Joe, Fat Pat, Frayser Boy, Gorilla Zoe, Gucci Mane, hallucinations, Heroin, histamine, Jae Millz, Jim Jones, Kanye West, ketamine, lean, Lil Boosie, Lil' Flip, Lil' Wayne, Lil' Wyte, Lou Bega, Ludacris, Mac Miller, Mack Maine, methadone, Mike Jones, opiates, Papoose, Paul Wall, PCP, phenothiazine antihistamine, Plies, Project Pat, promethazine, promo, purple Drank, purple sprite, Rick Ross, sizzurp, Slim Thug, Suboxone, T.I., The Game, Three 6 Mafia, Trae, Treatment, UGK, withdrawal, Yelawolf, Young Buck, Youngbloodz, Z-RO is operated by Recovery Brands LLC, a subsidiary of American Addiction Centers, Inc.
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